Ontology highlight
ABSTRACT:
SUBMITTER: Balagadde FK
PROVIDER: S-EPMC2387235 | biostudies-literature | 2008
REPOSITORIES: biostudies-literature
Balagaddé Frederick K FK Song Hao H Ozaki Jun J Collins Cynthia H CH Barnet Matthew M Arnold Frances H FH Quake Stephen R SR You Lingchong L
Molecular systems biology 20080415
We have constructed a synthetic ecosystem consisting of two Escherichia coli populations, which communicate bi-directionally through quorum sensing and regulate each other's gene expression and survival via engineered gene circuits. Our synthetic ecosystem resembles canonical predator-prey systems in terms of logic and dynamics. The predator cells kill the prey by inducing expression of a killer protein in the prey, while the prey rescue the predators by eliciting expression of an antidote prote ...[more]