Ontology highlight
ABSTRACT:
SUBMITTER: Schenk G
PROVIDER: S-EPMC2390564 | biostudies-literature | 2008 Apr
REPOSITORIES: biostudies-literature
Schenk Gundolf G Margraf Thomas T Torda Andrew E AE
Algorithms for molecular biology : AMB 20080401
<h4>Background</h4>Protein structure alignments are usually based on very different techniques to sequence alignments. We propose a method which treats sequence, structure and even combined sequence + structure in a single framework. Using a probabilistic approach, we calculate a similarity measure which can be applied to fragments containing only protein sequence, structure or both simultaneously.<h4>Results</h4>Proof-of-concept results are given for the different problems. For sequence alignme ...[more]