Ontology highlight
ABSTRACT:
SUBMITTER: Outchkourov NS
PROVIDER: S-EPMC2393789 | biostudies-literature | 2008 Mar
REPOSITORIES: biostudies-literature
Outchkourov Nikolay S NS Roeffen Will W Kaan Anita A Jansen Josephine J Luty Adrian A Schuiffel Danielle D van Gemert Geert Jan GJ van de Vegte-Bolmer Marga M Sauerwein Robert W RW Stunnenberg Hendrik G HG
Proceedings of the National Academy of Sciences of the United States of America 20080310 11
Malaria kills >1 million people each year, in particular in sub-Saharan Africa. Although asexual forms are directly responsible for disease and death, sexual stages account for the transmission of Plasmodium parasites from human to the mosquito vector and therefore the spread of the parasite in the population. Development of a malaria vaccine is urgently needed to reduce morbidity and mortality. Vaccines against sexual stages of Plasmodium falciparum are meant to decrease the force of transmissi ...[more]