LongSAGE profiling of nine human embryonic stem cell lines.
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ABSTRACT:
SUBMITTER: Hirst M
PROVIDER: S-EPMC2394759 | biostudies-literature | 2007
REPOSITORIES: biostudies-literature
Publications
LongSAGE profiling of nine human embryonic stem cell lines.
Hirst Martin M Delaney Allen A Rogers Sean A SA Schnerch Angelique A Persaud Deryck R DR O'Connor Michael D MD Zeng Thomas T Moksa Michelle M Fichter Keith K Mah Diana D Go Anne A Morin Ryan D RD Baross Agnes A Zhao Yongjun Y Khattra Jaswinder J Prabhu Anna-Liisa AL Pandoh Pawan P McDonald Helen H Asano Jennifer J Dhalla Noreen N Ma Kevin K Lee Stephanie S Ally Adrian A Chahal Neil N Menzies Stephanie S Siddiqui Asim A Holt Robert R Jones Steven S Gerhard Daniela S DS Thomson James A JA Eaves Connie J CJ Marra Marco A MA
Genome biology 20070101 6
To facilitate discovery of novel human embryonic stem cell (ESC) transcripts, we generated 2.5 million LongSAGE tags from 9 human ESC lines. Analysis of this data revealed that ESCs express proportionately more RNA binding proteins compared with terminally differentiated cells, and identified novel ESC transcripts, at least one of which may represent a marker of the pluripotent state. ...[more]
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