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Use of murine norovirus as a surrogate to evaluate resistance of human norovirus to disinfectants.


ABSTRACT: Murine norovirus (MNV) was used as a surrogate to study resistance of human norovirus to disinfectants used in hospitals. MNV was sensitive to alcohol, alcohol hand rubs, bleach, and povidone iodine-based disinfectant. Real-time reverse transcription-PCR results indicated that the presence of viral RNA did not correlate with the presence of infectious virus.

SUBMITTER: Belliot G 

PROVIDER: S-EPMC2394958 | biostudies-literature | 2008 May

REPOSITORIES: biostudies-literature

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Use of murine norovirus as a surrogate to evaluate resistance of human norovirus to disinfectants.

Belliot Gaël G   Lavaux Amandine A   Souihel Donya D   Agnello Davide D   Pothier Pierre P  

Applied and environmental microbiology 20080331 10


Murine norovirus (MNV) was used as a surrogate to study resistance of human norovirus to disinfectants used in hospitals. MNV was sensitive to alcohol, alcohol hand rubs, bleach, and povidone iodine-based disinfectant. Real-time reverse transcription-PCR results indicated that the presence of viral RNA did not correlate with the presence of infectious virus. ...[more]

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