High-resolution analysis of condition-specific regulatory modules in Saccharomyces cerevisiae.
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ABSTRACT:
SUBMITTER: Lee HG
PROVIDER: S-EPMC2395236 | biostudies-literature | 2008 Jan
REPOSITORIES: biostudies-literature
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High-resolution analysis of condition-specific regulatory modules in Saccharomyces cerevisiae.
Lee Hun-Goo HG Lee Hyo-Soo HS Jeon Sang-Hoon SH Chung Tae-Hoon TH Lim Young-Sung YS Huh Won-Ki WK
Genome biology 20080103 1
We present an approach for identifying condition-specific regulatory modules by using separate units of gene expression profiles along with ChIP-chip and motif data from Saccharomyces cerevisiae. By investigating the unique and common features of the obtained condition-specific modules, we detected several important properties of transcriptional network reorganization. Our approach reveals the functionally distinct coregulated submodules embedded in a coexpressed gene module and provides an effe ...[more]
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