Ontology highlight
ABSTRACT:
SUBMITTER: Kucherenko MM
PROVIDER: S-EPMC2398783 | biostudies-literature | 2008 Jun
REPOSITORIES: biostudies-literature
Kucherenko Mariya M MM Pantoja Mario M Yatsenko Andriy S AS Shcherbata Halyna R HR Fischer Karin A KA Maksymiv Dariya V DV Chernyk Yaroslava I YI Ruohola-Baker Hannele H
PloS one 20080611 6
The Dystroglycan-Dystrophin (Dg-Dys) complex has a capacity to transmit information from the extracellular matrix to the cytoskeleton inside the cell. It is proposed that this interaction is under tight regulation; however the signaling/regulatory components of Dg-Dys complex remain elusive. Understanding the regulation of the complex is critical since defects in this complex cause muscular dystrophy in humans. To reveal new regulators of the Dg-Dys complex, we used a model organism Drosophila m ...[more]