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Genetic and epigenetic analyses of MBD3 in colon and lung cancer.


ABSTRACT: MBD3: is a member of the methyl-CpG-binding domain family and is located on chromosome 19p13.3, a region of loss of heterozygosity in colon and lung cancers. We therefore screened samples for abnormalities in MBD3. Our results indicate that MBD3 is not a major target of genetic and epigenetic alteration in these cancers.

SUBMITTER: Zhu Y 

PROVIDER: S-EPMC2410281 | biostudies-literature | 2004 May

REPOSITORIES: biostudies-literature

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Genetic and epigenetic analyses of MBD3 in colon and lung cancer.

Zhu Y Y   Harrison D J DJ   Bader S A SA  

British journal of cancer 20040501 10


MBD3: is a member of the methyl-CpG-binding domain family and is located on chromosome 19p13.3, a region of loss of heterozygosity in colon and lung cancers. We therefore screened samples for abnormalities in MBD3. Our results indicate that MBD3 is not a major target of genetic and epigenetic alteration in these cancers. ...[more]

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