Ontology highlight
ABSTRACT:
SUBMITTER: Doi Y
PROVIDER: S-EPMC2415784 | biostudies-literature | 2008 Jun
REPOSITORIES: biostudies-literature
Antimicrobial agents and chemotherapy 20080324 6
A chromosomally encoded class D beta-lactamase, OXA-114, was characterized from Achromobacter xylosoxidans strain CIP69598. beta-Lactamase OXA-114 shared 56% amino acid identity with the naturally occurring class D beta-lactamase of Burkholderia cenocepacia and 42% identity with the acquired oxacillinases OXA-9 and OXA-18. OXA-114 has a narrow-spectrum hydrolysis profile, although it includes imipenem, at a very low level. PCR and sequencing revealed that bla(OXA-114)-like genes were identified ...[more]