Ontology highlight
ABSTRACT:
SUBMITTER: Hughes JL
PROVIDER: S-EPMC2423095 | biostudies-literature | 2008 Jun
REPOSITORIES: biostudies-literature
Hughes Jessica L JL Nolder Christi L CL Nowalk Andrew J AJ Clifton Dawn R DR Howison Rebekah R RR Schmit Virginia L VL Gilmore Robert D RD Carroll James A JA
Infection and immunity 20080407 6
Borrelia burgdorferi, the causative agent of Lyme disease in the United States, regulates numerous genes encoding lipoproteins on linear plasmid 54 in response to environmental cues. We analyzed a subset of these genes/proteins that were historically categorized as paralogous gene family 54 (BBA64, BBA65, BBA66, BBA68, BBA69, BBA70, BBA71, and BBA73) and found that the expression of several genes was influenced by the sigma(N)-sigma(S) regulatory cascade at the level of transcription and protein ...[more]