Ontology highlight
ABSTRACT:
SUBMITTER: Terwilliger TC
PROVIDER: S-EPMC2424225 | biostudies-literature | 2008 May
REPOSITORIES: biostudies-literature
Terwilliger Thomas C TC Grosse-Kunstleve Ralf W RW Afonine Pavel V PV Moriarty Nigel W NW Adams Paul D PD Read Randy J RJ Zwart Peter H PH Hung Li-Wei LW
Acta crystallographica. Section D, Biological crystallography 20080419 Pt 5
A procedure for carrying out iterative model building, density modification and refinement is presented in which the density in an OMIT region is essentially unbiased by an atomic model. Density from a set of overlapping OMIT regions can be combined to create a composite 'iterative-build' OMIT map that is everywhere unbiased by an atomic model but also everywhere benefiting from the model-based information present elsewhere in the unit cell. The procedure may have applications in the validation ...[more]