A Bayesian evaluation of human mitochondrial substitution rates.
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ABSTRACT:
SUBMITTER: Endicott P
PROVIDER: S-EPMC2427281 | biostudies-literature | 2008 Apr
REPOSITORIES: biostudies-literature
Publications
A Bayesian evaluation of human mitochondrial substitution rates.
Endicott Phillip P Ho Simon Y W SY
American journal of human genetics 20080327 4
Accurate estimates of mitochondrial substitution rates are central to molecular studies of human evolution, but meaningful comparisons of published studies are problematic because of the wide range of methodologies and data sets employed. These differences are nowhere more pronounced than among rates estimated from phylogenies, genealogies, and pedigrees. By using a data set comprising mitochondrial genomes from 177 humans, we estimate substitution rates for various data partitions by using Baye ...[more]
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