A novel regulatory protein governing biofilm formation in Bacillus subtilis.
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ABSTRACT:
SUBMITTER: Chu F
PROVIDER: S-EPMC2430766 | biostudies-literature | 2008 Jun
REPOSITORIES: biostudies-literature
Publications
A novel regulatory protein governing biofilm formation in Bacillus subtilis.
Chu Frances F Kearns Daniel B DB McLoon Anna A Chai Yunrong Y Kolter Roberto R Losick Richard R
Molecular microbiology 20080421 5
Production of an extracellular matrix is a hallmark of biofilm formation. In the spore-forming bacterium Bacillus subtilis, the matrix consists of an exopolysaccharide, which is specified by the epsA-O operon, and a secreted protein TasA, which is encoded by the yqxM-sipW-tasA operon. Past and present evidence establish that the epsA-O and yqxM-sipW-tasA operons are controlled by the repressor proteins SinR and AbrB. Here, we report the identification of a novel regulatory protein Slr that promo ...[more]
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