Ontology highlight
ABSTRACT:
SUBMITTER: Pare G
PROVIDER: S-EPMC2432033 | biostudies-literature | 2008 Jul
REPOSITORIES: biostudies-literature
PLoS genetics 20080704 7
While circulating levels of soluble Intercellular Adhesion Molecule 1 (sICAM-1) have been associated with diverse conditions including myocardial infarction, stroke, malaria, and diabetes, comprehensive analysis of the common genetic determinants of sICAM-1 is not available. In a genome-wide association study conducted among 6,578 participants in the Women's Genome Health Study, we find that three SNPs at the ICAM1 (19p13.2) locus (rs1799969, rs5498 and rs281437) are non-redundantly associated w ...[more]