Ontology highlight
ABSTRACT:
SUBMITTER: Gao X
PROVIDER: S-EPMC2438614 | biostudies-literature | 2008 Jul
REPOSITORIES: biostudies-literature
Gao Xiaohong X Yeo Kim Pin KP Aw Siqi Sharon SS Kuss Claudia C Iyer Jayasree K JK Genesan Saraswathy S Rajamanonmani Ravikumar R Lescar Julien J Bozdech Zbynek Z Preiser Peter R PR
PLoS pathogens 20080711 7
Invasion by the malaria merozoite depends on recognition of specific erythrocyte surface receptors by parasite ligands. Plasmodium falciparum uses multiple ligands, including at least two gene families, reticulocyte binding protein homologues (RBLs) and erythrocyte binding proteins/ligands (EBLs). The combination of different RBLs and EBLs expressed in a merozoite defines the invasion pathway utilized and could also play a role in parasite virulence. The binding regions of EBLs lie in a conserve ...[more]