Ontology highlight
ABSTRACT:
SUBMITTER: Affara M
PROVIDER: S-EPMC2440409 | biostudies-literature | 2007 Aug
REPOSITORIES: biostudies-literature
Affara Muna M Dunmore Benjamin B Savoie Christopher C Imoto Seiya S Tamada Yoshinori Y Araki Hiromitsu H Charnock-Jones D Stephen DS Miyano Satoru S Print Cristin C
Philosophical transactions of the Royal Society of London. Series B, Biological sciences 20070801 1484
Endothelial cell (EC) apoptosis may play an important role in blood vessel development, homeostasis and remodelling. In support of this concept, EC apoptosis has been detected within remodelling vessels in vivo, and inactivation of EC apoptosis regulators has caused dramatic vascular phenotypes. EC apoptosis has also been associated with cardiovascular pathologies. Therefore, understanding the regulation of EC apoptosis, with the goal of intervening in this process, has become a current research ...[more]