Ontology highlight
ABSTRACT:
SUBMITTER: Schmidt-Chanasit J
PROVIDER: S-EPMC2446866 | biostudies-literature | 2008 Jun
REPOSITORIES: biostudies-literature
Schmidt-Chanasit Jonas J Bleymehl Karoline K Rabenau Holger F HF Ulrich Rainer G RG Cinatl Jindrich J Doerr Hans Wilhelm HW
Journal of clinical microbiology 20080409 6
Here we describe for the first time the productive in vitro infection of human retinal pigment epithelial cells by varicella-zoster virus (VZV), resulting in a typical cytopathic effect (CPE) that is characterized by enlarged cells with increased granularity. Depending on the CPE dissemination, high titers of up to 1.6 x 10(6) PFU of cell-free and cryostable VZV/ml can be recovered. ...[more]