Ontology highlight
ABSTRACT:
SUBMITTER: Garcia-Boronat M
PROVIDER: S-EPMC2447719 | biostudies-literature | 2008 Jul
REPOSITORIES: biostudies-literature
Garcia-Boronat Maria M Diez-Rivero Carmen M CM Reinherz Ellis L EL Reche Pedro A PA
Nucleic acids research 20080427 Web Server issue
We have developed PVS (Protein Variability Server), a web-based tool that uses several variability metrics to compute the absolute site variability in multiple protein-sequence alignments (MSAs). The variability is then assigned to a user-selected reference sequence consisting of either the first sequence in the alignment or a consensus sequence. Subsequently, PVS performs tasks that are relevant for structure-function studies, such as plotting and visualizing the variability in a relevant 3D-st ...[more]