Ontology highlight
ABSTRACT:
SUBMITTER: Wu GK
PROVIDER: S-EPMC2447869 | biostudies-literature | 2008 Apr
REPOSITORIES: biostudies-literature
Neuron 20080401 1
Cortical inhibition plays an important role in shaping neuronal processing. The underlying synaptic mechanisms remain controversial. Here, in vivo whole-cell recordings from neurons in the rat primary auditory cortex revealed that the frequency tuning curve of inhibitory input was broader than that of excitatory input. This results in relatively stronger inhibition in frequency domains flanking the preferred frequencies of the cell and a significant sharpening of the frequency tuning of membrane ...[more]