Evaluation of EGR1 as a candidate gene for high myopia.
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ABSTRACT:
SUBMITTER: Li T
PROVIDER: S-EPMC2464612 | biostudies-literature | 2008
REPOSITORIES: biostudies-literature
Publications
Evaluation of EGR1 as a candidate gene for high myopia.
Li Tuo T Xiao Xueshan X Li Shiqiang S Xing Yiqiao Y Guo Xiangming X Zhang Qingjiong Q
Molecular vision 20080715
<h4>Purpose</h4>EGR1 (OMIM 128990) is an early growth response gene that has been shown to be related to myopia by upregulation and down-regulation of axial eye growth in experimentally induced chicken myopia and knockout mice. The purpose of this study was to test whether variations in the human EGR1 gene are related to high myopia.<h4>Methods</h4>Genomic DNA was prepared from leukocytes of peripheral blood. Cycle sequencing was used to detect sequence variations in EGR1.<h4>Results</h4>No path ...[more]
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