Ontology highlight
ABSTRACT:
SUBMITTER: Jurica MS
PROVIDER: S-EPMC2474778 | biostudies-literature | 2008 Jun
REPOSITORIES: biostudies-literature
Current opinion in structural biology 20080610 3
The spliceosome is the huge macromolecular assembly responsible for the removal of introns from pre-mRNA transcripts. The size and complexity of this dynamic cellular machine dictate that structural analysis of the spliceosome is best served by a combination of techniques. Electron microscopy is providing a more global, albeit less detailed, view of spliceosome assemblies. X-ray crystallographers and NMR spectroscopists are steadily reporting more atomic resolution structures of individual splic ...[more]