Ontology highlight
ABSTRACT:
SUBMITTER: Russell DJ
PROVIDER: S-EPMC2478692 | biostudies-literature | 2008 Jul
REPOSITORIES: biostudies-literature
Russell David J DJ Otu Hasan H HH Sayood Khalid K
BMC bioinformatics 20080710
<h4>Background</h4>We propose a multiple sequence alignment (MSA) algorithm and compare the alignment-quality and execution-time of the proposed algorithm with that of existing algorithms. The proposed progressive alignment algorithm uses a grammar-based distance metric to determine the order in which biological sequences are to be pairwise aligned. The progressive alignment occurs via pairwise aligning new sequences with an ensemble of the sequences previously aligned.<h4>Results</h4>The perfor ...[more]