Ontology highlight
ABSTRACT:
SUBMITTER: Xue Y
PROVIDER: S-EPMC2481379 | biostudies-literature | 2008 Jul
REPOSITORIES: biostudies-literature
Xue Yuan Y Cao Renhai R Nilsson Daniel D Chen Shaohua S Westergren Rickard R Hedlund Eva-Maria EM Martijn Cecile C Rondahl Lena L Krauli Per P Walum Erik E Enerbäck Sven S Cao Yihai Y
Proceedings of the National Academy of Sciences of the United States of America 20080711 29
Adipogenesis is spatiotemporally coupled to angiogenesis throughout adult life, and the interplay between these two processes is communicated by multiple factors. Here we show that in a transgenic mouse model, increased expression of forkhead box C2 (FOXC2) in the adipose tissue affects angiogenesis, vascular patterning, and functions. White and brown adipose tissues contain a considerably high density of microvessels appearing as vascular plexuses, which show redistribution of vascular smooth m ...[more]