Ontology highlight
ABSTRACT:
SUBMITTER: Mooney SD
PROVIDER: S-EPMC2483305 | biostudies-literature | 2005 Dec
REPOSITORIES: biostudies-literature
Mooney Sean D SD Liang Mike Hsin-Ping MH DeConde Rob R Altman Russ B RB
Proteins 20051201 4
A primary challenge for structural genomics is the automated functional characterization of protein structures. We have developed a sequence-independent method called S-BLEST (Structure-Based Local Environment Search Tool) for the annotation of previously uncharacterized protein structures. S-BLEST encodes the local environment of an amino acid as a vector of structural property values. It has been applied to all amino acids in a nonredundant database of protein structures to generate a searchab ...[more]