Ontology highlight
ABSTRACT:
SUBMITTER: McKasson MJ
PROVIDER: S-EPMC2483403 | biostudies-literature | 2008 Jun
REPOSITORIES: biostudies-literature
McKasson Marilyn J MJ Huang Ling L Robinson Kenneth R KR
Experimental neurology 20080305 2
Little is known about the cues that guide migrating neural crest derivatives to their targets. This lack of understanding is especially significant in the case of Schwann cells, which have been transplanted into the central nervous system in an effort to promote axonal myelination after injury or disease. We have investigated the response of Schwann cells, cultured from the peripheral nerves of E7/8 chick embryos, to applied electrical fields. We find that they respond by migrating to the anode, ...[more]