Ontology highlight
ABSTRACT:
SUBMITTER: Szczesny P
PROVIDER: S-EPMC2483945 | biostudies-literature | 2008
REPOSITORIES: biostudies-literature
Szczesny Pawel P Linke Dirk D Ursinus Astrid A Bär Kerstin K Schwarz Heinz H Riess Tanja M TM Kempf Volkhard A J VA Lupas Andrei N AN Martin Jörg J Zeth Kornelius K
PLoS pathogens 20080808 8
Trimeric autotransporter adhesins (TAAs) are a major class of proteins by which pathogenic proteobacteria adhere to their hosts. Prominent examples include Yersinia YadA, Haemophilus Hia and Hsf, Moraxella UspA1 and A2, and Neisseria NadA. TAAs also occur in symbiotic and environmental species and presumably represent a general solution to the problem of adhesion in proteobacteria. The general structure of TAAs follows a head-stalk-anchor architecture, where the heads are the primary mediators o ...[more]