Global challenges in the development and delivery of paediatric antiretrovirals.
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ABSTRACT:
SUBMITTER: Bowen A
PROVIDER: S-EPMC2491451 | biostudies-literature | 2008 Jun
REPOSITORIES: biostudies-literature
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Global challenges in the development and delivery of paediatric antiretrovirals.
Bowen Asha A Palasanthiran Pamela P Sohn Annette H AH
Drug discovery today 20080505 11-12
By the end of 2006, compared with 28% coverage for adults, only 15% of children with HIV that needed antiretroviral treatment were receiving it. Major challenges in delivering treatment include the lack of paediatric antiretrovirals that can be dosed in small children and limited studies examining safety and efficacy for existing antiretroviral formulations. The high costs of treatment have been reduced through the use of generic, fixed-dose combination drugs. Evidence-based strategies for manag ...[more]
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