Molecular characterization of ofloxacin-resistant Mycobacterium tuberculosis strains from Russia.
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ABSTRACT:
SUBMITTER: Mokrousov I
PROVIDER: S-EPMC2493099 | biostudies-literature | 2008 Aug
REPOSITORIES: biostudies-literature
Publications
Molecular characterization of ofloxacin-resistant Mycobacterium tuberculosis strains from Russia.
Mokrousov Igor I Otten Tatiana T Manicheva Olga O Potapova Yulia Y Vishnevsky Boris B Narvskaya Olga O Rastogi Nalin N
Antimicrobial agents and chemotherapy 20080616 8
In this work, we studied the variation in the gyrA and gyrB genes in ofloxacin- and multidrug-resistant Mycobacterium tuberculosis strains circulating in northwest Russia. Comparison with spoligotyping data suggested that similar to the spread of multidrug-resistant tuberculosis, the spread of fluoroquinolone-resistant tuberculosis in Russia may be due, at least partly, to the prevalence of the Beijing genotype in a local population of M. tuberculosis. ...[more]
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