Ontology highlight
ABSTRACT:
SUBMITTER: Fu Y
PROVIDER: S-EPMC2493132 | biostudies-literature | 2008 Aug
REPOSITORIES: biostudies-literature
Antimicrobial agents and chemotherapy 20080527 8
Resistance to ciprofloxacin was detected in 111 (48.1%) isolates of Klebsiella pneumoniae from China. GyrA alterations were identified in the ciprofloxacin-resistant and ciprofloxacin-susceptible isolates. The results, including previously published data, indicate that the single substitution Ser83-->Ile and three types of double mutations at Ser83 and Asp87 were required for ciprofloxacin resistance (P < 0.05). ...[more]