Ontology highlight
ABSTRACT:
SUBMITTER: Bagnoli F
PROVIDER: S-EPMC2493256 | biostudies-literature | 2008 Aug
REPOSITORIES: biostudies-literature
Bagnoli Fabio F Moschioni Monica M Donati Claudio C Dimitrovska Valentina V Ferlenghi Ilaria I Facciotti Claudia C Muzzi Alessandro A Giusti Fabiola F Emolo Carla C Sinisi Antonella A Hilleringmann Markus M Pansegrau Werner W Censini Stefano S Rappuoli Rino R Covacci Antonello A Masignani Vega V Barocchi Michele A MA
Journal of bacteriology 20080530 15
Analysis of publicly available genomes of Streptococcus pneumoniae has led to the identification of a new genomic element containing genes typical of gram-positive pilus islets (PIs). Here, we demonstrate that this genomic region, herein referred to as PI-2 (consisting of pitA, sipA, pitB, srtG1, and srtG2) codes for a second functional pilus in pneumococcus. Polymerization of the PI-2 pilus requires the backbone protein PitB as well as the sortase SrtG1 and the signal peptidase-like protein Sip ...[more]