Ontology highlight
ABSTRACT:
SUBMITTER: Mavrich TN
PROVIDER: S-EPMC2493396 | biostudies-literature | 2008 Jul
REPOSITORIES: biostudies-literature
Genome research 20080612 7
Most nucleosomes are well-organized at the 5' ends of S. cerevisiae genes where "-1" and "+1" nucleosomes bracket a nucleosome-free promoter region (NFR). How nucleosomal organization is specified by the genome is less clear. Here we establish and inter-relate rules governing genomic nucleosome organization by sequencing DNA from more than one million immunopurified S. cerevisiae nucleosomes (displayed at http://atlas.bx.psu.edu/). Evidence is presented that the organization of nucleosomes throu ...[more]