Ontology highlight
ABSTRACT:
SUBMITTER: Wederell ED
PROVIDER: S-EPMC2504304 | biostudies-literature | 2008 Aug
REPOSITORIES: biostudies-literature
Wederell Elizabeth D ED Bilenky Mikhail M Cullum Rebecca R Thiessen Nina N Dagpinar Melis M Delaney Allen A Varhol Richard R Zhao YongJun Y Zeng Thomas T Bernier Bridget B Ingham Matthew M Hirst Martin M Robertson Gordon G Marra Marco A MA Jones Steven S Hoodless Pamela A PA
Nucleic acids research 20080708 14
Foxa2 (HNF3 beta) is a one of three, closely related transcription factors that are critical to the development and function of the mouse liver. We have used chromatin immunoprecipitation and massively parallel Illumina 1G sequencing (ChIP-Seq) to create a genome-wide profile of in vivo Foxa2-binding sites in the adult liver. More than 65% of the approximately 11.5 k genomic sites associated with Foxa2 binding, mapped to extended gene regions of annotated genes, while more than 30% of intragenic ...[more]