Ontology highlight
ABSTRACT:
SUBMITTER: Katoh K
PROVIDER: S-EPMC25163 | biostudies-literature | 1999 Jan
REPOSITORIES: biostudies-literature
Katoh K K Hammar K K Smith P J PJ Oldenbourg R R
Molecular biology of the cell 19990101 1
We have investigated the dynamic behavior of cytoskeletal fine structure in the lamellipodium of nerve growth cones using a new type of polarized light microscope (the Pol-Scope). Pol-Scope images display with exquisite resolution and definition birefringent fine structures, such as filaments and membranes, without having to treat the cell with exogenous dyes or fluorescent labels. Furthermore, the measured birefringence of protein fibers in the thin lamellipodial region can be interpreted in te ...[more]