Ontology highlight
ABSTRACT:
SUBMITTER: Livesay EA
PROVIDER: S-EPMC2516349 | biostudies-literature | 2008 Jan
REPOSITORIES: biostudies-literature
Livesay Eric A EA Tang Keqi K Taylor Beverley K BK Buschbach Michael A MA Hopkins Derek F DF LaMarche Brian L BL Zhao Rui R Shen Yufeng Y Orton Daniel J DJ Moore Ronald J RJ Kelly Ryan T RT Udseth Harold R HR Smith Richard D RD
Analytical chemistry 20071129 1
We describe a four-column, high-pressure capillary liquid chromatography (LC) system for robust, high-throughput liquid chromatography-mass spectrometry (LC-MS(/MS)) analyses. This system performs multiple LC separations in parallel, but staggers each of them such that the data-rich region of each separation is sampled sequentially. By allowing nearly continuous data acquisition, this design maximizes the use of the mass spectrometer. Each analytical column is connected to a corresponding ESI em ...[more]