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A catalytic asymmetric vinylogous Mukaiyama aldol reaction.

ABSTRACT: A vinylogous Mukaiyama aldol reaction, conducted using 10 mol % of a BITIP catalyst and B(OMe)3 as an additive, effects an enantioselective four-carbon chain extension to give versatile E-alpha,beta-unsaturated thiol esters.

SUBMITTER: Heumann LV

PROVIDER: S-EPMC2516376 | biostudies-literature | 2007 Oct

REPOSITORIES: biostudies-literature

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A catalytic asymmetric vinylogous Mukaiyama aldol reaction.

Heumann Lars V LV Keck Gary E GE

Organic letters 20070921 21

A vinylogous Mukaiyama aldol reaction, conducted using 10 mol % of a BITIP catalyst and B(OMe)3 as an additive, effects an enantioselective four-carbon chain extension to give versatile E-alpha,beta-unsaturated thiol esters. ...[more]

PMID: 17887693

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