Successful choice behavior is associated with distinct and coherent network states in anterior cingulate cortex.

ABSTRACT: Successful decision making requires an ability to monitor contexts, actions, and outcomes. The anterior cingulate cortex (ACC) is thought to be critical for these functions, monitoring and guiding decisions especially in challenging situations involving conflict and errors. A number of different single-unit correlates have been observed in the ACC that reflect the diverse cognitive components involved. Yet how ACC neurons function as an integrated network is poorly understood. Here we show, using advanced population analysis of multiple single-unit recordings from the rat ACC during performance of an ecologically valid decision-making task, that ensembles of neurons move through different coherent and dissociable states as the cognitive requirements of the task change. This organization in

SUBMITTER: Lapish CC 

PROVIDER: S-EPMC2516968 | biostudies-literature | 2008 Aug

REPOSITORIES: biostudies-literature