Ontology highlight
ABSTRACT:
SUBMITTER: Baruch L
PROVIDER: S-EPMC2517614 | biostudies-literature | 2008
REPOSITORIES: biostudies-literature
Baruch Leehod L Itzkovitz Shalev S Golan-Mashiach Michal M Shapiro Ehud E Segal Eran E
PLoS computational biology 20080711 7
Synaptic wiring of neurons in Caenorhabditis elegans is largely invariable between animals. It has been suggested that this feature stems from genetically encoded molecular markers that guide the neurons in the final stage of synaptic formation. Identifying these markers and unraveling the logic by which they direct synapse formation is a key challenge. Here, we address this task by constructing a probabilistic model that attempts to explain the neuronal connectivity diagram of C. elegans as a f ...[more]