Ontology highlight
ABSTRACT:
SUBMITTER: Dror O
PROVIDER: S-EPMC2525628 | biostudies-literature | 2008 Jul
REPOSITORIES: biostudies-literature
Dror Oranit O Schneidman-Duhovny Dina D Shulman-Peleg Alexandra A Nussinov Ruth R Wolfson Haim J HJ Sharan Roded R
BMC systems biology 20080731
<h4>Background</h4>The study of gene mutants and their interactions is fundamental to understanding gene function and backup mechanisms within the cell. The recent availability of large scale genetic interaction networks in yeast and worm allows the investigation of the biological mechanisms underlying these interactions at a global scale. To date, less than 2% of the known genetic interactions in yeast or worm can be accounted for by sequence similarity.<h4>Results</h4>Here, we perform a genome ...[more]