Ontology highlight
ABSTRACT:
SUBMITTER: Pistiner M
PROVIDER: S-EPMC2525650 | biostudies-literature | 2008 Jul
REPOSITORIES: biostudies-literature
Pistiner Michael M Hunninghake Gary M GM Soto-Quiros Manuel E ME Avila Lydiana L Murphy Amy A Lasky-Su Jessica J Schuemann Brooke B Klanderman Barbara J BJ Raby Benjamin A BA Celedón Juan C JC
Clinical and molecular allergy : CMA 20080731
<h4>Background</h4>IL12A has been implicated in T-cell development and may thus influence the development of atopy and allergic diseases.<h4>Methods</h4>We tested for association between four linkage disequilibrium (LD)-tagging SNPs (rs2243123, rs2243151, rs668998, and rs17826053) in IL12A and asthma and allergy-related (serum total and allergen-specific IgE, and skin test reactivity [STR] to two common allergens) phenotypes in two samples: 417 Costa Rican children with asthma and their parents, ...[more]