Ontology highlight
ABSTRACT:
SUBMITTER: Cheong JY
PROVIDER: S-EPMC2526506 | biostudies-literature | 2008 Feb
REPOSITORIES: biostudies-literature
Cheong Jae Youn JY Cho Sung Won SW Lee Jung A JA Lee Kwang Jae KJ Wang Hee Jung HJ Lee Jong Eun JE Kim Jin Hong JH
Journal of Korean medical science 20080201 1
The reasons for the viral persistence of hepatitis B virus (HBV) infection are unknown, but are probably related to host immune factors. Several matrix metalloproteinases (MMPs) can regulate an inflammatory response. The aim of this study was to assess the effects of the single nucleotide polymorphisms (SNPs) of MMP-3 and -9 genes on the susceptibility to persistent HBV infection. We studied 489 Korean patients with HBV infection (144 inactive carriers, 182 chronic hepatitis, and 163 liver cirrh ...[more]