Ontology highlight
ABSTRACT:
SUBMITTER: Tran MK
PROVIDER: S-EPMC2527020 | biostudies-literature | 2008
REPOSITORIES: biostudies-literature
Tran Michael K MK Schultz Carolyn J CJ Baumann Ute U
BMC genomics 20080731
<h4>Background</h4>Upstream open reading frames (uORFs) can down-regulate the translation of the main open reading frame (mORF) through two broad mechanisms: ribosomal stalling and reducing reinitiation efficiency. In distantly related plants, such as rice and Arabidopsis, it has been found that conserved uORFs are rare in these transcriptomes with approximately 100 loci. It is unclear how prevalent conserved uORFs are in closely related plants.<h4>Results</h4>We used a homology-based approach t ...[more]