Multicellular sprouting in vitro.
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ABSTRACT:
SUBMITTER: Szabo A
PROVIDER: S-EPMC2527280 | biostudies-literature | 2008 Sep
REPOSITORIES: biostudies-literature
Publications
Multicellular sprouting in vitro.
Szabo Andras A Mehes Elod E Kosa Edina E Czirok Andras A
Biophysical journal 20080620 6
Cell motility and its guidance through cell-cell contacts is instrumental in vasculogenesis and in other developmental or pathological processes as well. During vasculogenesis, multicellular sprouts invade rapidly into avascular areas, eventually creating a polygonal pattern. Sprout elongation, in turn, depends on a continuous supply of endothelial cells, streaming along the sprout toward its tip. As long-term videomicroscopy of in vitro cell cultures reveal, cell lines such as C6 gliomas or 3T3 ...[more]
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