Ontology highlight
ABSTRACT:
SUBMITTER: Kotakadi VS
PROVIDER: S-EPMC2527648 | biostudies-literature | 2008 Sep
REPOSITORIES: biostudies-literature
Kotakadi Venkata S VS Jin Yu Y Hofseth Anne B AB Ying Lei L Cui Xiangli X Volate Suresh S Chumanevich Alexander A Wood Patricia A PA Price Robert L RL McNeal Anna A Singh Udai P UP Singh Narendra P NP Nagarkatti Mitzi M Nagarkatti Prakash S PS Matesic Lydia E LE Auclair Karine K Wargovich Michael J MJ Hofseth Lorne J LJ
Carcinogenesis 20080620 9
Ulcerative colitis is a dynamic, chronic inflammatory condition of the colon associated with an increased colon cancer risk. Ginkgo biloba is a putative antioxidant and has been used for thousands of years to treat a variety of ailments. The aim of this study was to test whether the standardized G.biloba extract, EGb 761, is an antioxidant that can be used to prevent and treat colitis in mice. Here, we show that EGb 761 suppresses the activation of macrophages and can be used to both prevent and ...[more]