Ontology highlight
ABSTRACT:
SUBMITTER: Bowman MJ
PROVIDER: S-EPMC2532755 | biostudies-literature | 2007 Aug
REPOSITORIES: biostudies-literature
Bowman Michael J MJ Zaia Joseph J
Analytical chemistry 20070703 15
Although stable isotopic labeling has found widespread use in the proteomics field, its application to carbohydrate quantification has been limited. Herein we report the design, synthesis, and application of a novel series of compounds that allow for the incorporation of isotopic variation within glycan structures. The novel feature of the compounds is the ability to incorporate the isotopes in a controlled manner, allowing for the generation of four tags that vary only in their isotopic content ...[more]