Dataset Information

Young maternal age and the risk of neonatal mortality in rural Nepal.

ABSTRACT: To investigate the relationship between adolescent pregnancy and neonatal mortality in a nutritionally deprived population in rural Nepal, and to determine mechanisms through which low maternal age may affect neonatal mortality.Nested cohort study using data from a population-based, cluster-randomized, placebo-controlled trial of newborn skin and umbilical cord cleansing with chlorhexidine.Sarlahi District of Nepal.Live-born singleton infants of mothers younger than 25 years who were either parity 0 or 1 (n = 10,745).Maternal age at birth of offspring.Crude and adjusted odds ratios of neonatal mortality by maternal age category.Infants born to mothers aged 12 to 15 years were at a higher risk of neonatal mortality than those born to women aged 20 to 24 years (odds ratio, 2.24; 95% confidence interval, 1.40-3.59). After adjustment for confounders, there was a 53% excess risk of neonatal mortality among infants born to mothers in the youngest vs oldest age category (1.53; 0.90-2.60). This association was attenuated on further adjustment for low birth weight, preterm birth, or small-for-gestational-age births.The higher risk of neonatal mortality among younger mothers in this setting is partially explained by differences in socioeconomic factors in younger vs older mothers; risk is mediated primarily through preterm delivery, low birth weight, newborns being small for gestational age, and/or some interaction of these variables.clinicaltrials.gov Identifier: NCT00109616.

SUBMITTER: Sharma V

PROVIDER: S-EPMC2535853 | biostudies-literature | 2008 Sep

REPOSITORIES: biostudies-literature

ACCESS DATA

Publications

Young maternal age and the risk of neonatal mortality in rural Nepal.

Sharma Vandana V Katz Joanne J Mullany Luke C LC Khatry Subarna K SK LeClerq Steven C SC Shrestha Sharada R SR Darmstadt Gary L GL Tielsch James M JM

Archives of pediatrics & adolescent medicine 20080901 9

<h4>Objectives</h4>To investigate the relationship between adolescent pregnancy and neonatal mortality in a nutritionally deprived population in rural Nepal, and to determine mechanisms through which low maternal age may affect neonatal mortality.<h4>Design</h4>Nested cohort study using data from a population-based, cluster-randomized, placebo-controlled trial of newborn skin and umbilical cord cleansing with chlorhexidine.<h4>Setting</h4>Sarlahi District of Nepal.<h4>Participants</h4>Live-born ...[more]

PMID: 18762599

Similar Datasets

Project description:Objective:To assess neonatal and under-five mortality and the health situation for children in Dolpa, a remote rural area of Nepal. Study design:Mixed methods: quantitative (retrospective cross sectional) and qualitative (semistructured interviews). Rationale:Progress in reducing child and newborn mortality in Nepal has reached the remote areas to a limited extent. Furthermore, there may be substantial under-reporting and data may be unreliable. Setting and participants:The population of Dolpa district is approximately 35 000. We visited 10 randomly selected villages (plus one settlement) with approximately 12 000 inhabitants. Methodology:Records of the number of deliveries, neonatal and under-five deaths were collected. 100 children (10 different villages) were evaluated for common diseases present during the month prior to the investigation. 20 interviews were conducted about the cultural perceptions of neonatal death and morbidity; in each village at least one interview was undertaken. Results:The population of the 10 villages (plus one settlement) under investigation was 12 287. 300 deliveries have taken place during the last 12 months before the study. There were 30 children reported to have died; out of those 20 were in the neonatal period. This reflects an estimated neonatal mortality rate in Dolpa district of 67/1000 live births (95% CI 41-101/1000) and an estimated under-five mortality rate of 100/1000 (95% CI 70-140/1000). In the previous month, out of 100 children surveyed there had been 11 cases of acute lower respiratory infection (ALRI), 7 cases of diarrhoea, 3 cases of isolated malnutrition and 5 cases of malnutrition combined with ALRI or diarrhoea.Based on qualitative interviews traditional beliefs still play a major role, and are partly a hindrance to progress in health. There is also mistrust in the health services and misconceptions about 'modern' medicine and treatment facilities. Conclusion:Despite progress in child morbidity and mortality in Nepal, some areas remain underserved by health services and neonatal mortality is far above the Nepalese average, which is 29/1000 live births. There is a substantial need to increase and train health staff. Health promotion should be encouraged but cultural perceptions have to be understood if positive behavioural change is to be achieved.

Dataset Information

Young maternal age and the risk of neonatal mortality in rural Nepal.

Publications

Young maternal age and the risk of neonatal mortality in rural Nepal.

Similar Datasets

OmicsDI is part of the ELIXIR infrastructure