PCR detection of type I polyketide synthase genes in myxobacteria.
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ABSTRACT:
SUBMITTER: Komaki H
PROVIDER: S-EPMC2546657 | biostudies-literature | 2008 Sep
REPOSITORIES: biostudies-literature
Publications
PCR detection of type I polyketide synthase genes in myxobacteria.
Komaki Hisayuki H Fudou Ryosuke R Iizuka Takashi T Nakajima Daisuke D Okazaki Koei K Shibata Daisuke D Ojika Makoto M Harayama Shigeaki S
Applied and environmental microbiology 20080707 17
The diversity of type I modular polyketide synthase (PKS) was explored by PCR amplification of DNA encoding ketosynthase and acyltransferase domains in myxobacteria. The sequencing of the amplicons revealed that many PKS genes were distantly related to the published sequences. Thus, myxobacteria may be excellent resources for novel and diverse polyketides. ...[more]
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