Ontology highlight
ABSTRACT:
SUBMITTER: Callaghan MJ
PROVIDER: S-EPMC2546767 | biostudies-literature | 2008 Sep
REPOSITORIES: biostudies-literature
Callaghan Martin J MJ Buckee Caroline C McCarthy Noel D ND Ibarz Pavón Ana Belén AB Jolley Keith A KA Faust Saul S Gray Stephen J SJ Kaczmarski Edward B EB Levin Michael M Kroll J Simon JS Maiden Martin C J MC Pollard Andrew J AJ
Journal of clinical microbiology 20080528 9
The meningococcal Opa proteins play an important role in pathogenesis by mediating invasion of human cells. The aim of this investigation was to determine whether carried and disease-associated meningococci possess different Opa repertoires and whether the diversity of these proteins is associated with clinical severity of disease. Opa repertoires in 227 disease-associated meningococci, isolated in the United Kingdom over a period of 6 years, were compared to the repertoires in 190 asymptomatica ...[more]