The F-like protein Ac23 enhances the infectivity of the budded virus of gp64-null Autographa californica multinucleocapsid nucleopolyhedrovirus pseudotyped with baculovirus envelope fusion protein F.
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ABSTRACT:
SUBMITTER: Wang M
PROVIDER: S-EPMC2546973 | biostudies-literature | 2008 Oct
REPOSITORIES: biostudies-literature
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The F-like protein Ac23 enhances the infectivity of the budded virus of gp64-null Autographa californica multinucleocapsid nucleopolyhedrovirus pseudotyped with baculovirus envelope fusion protein F.
Wang Manli M Tan Ying Y Yin Feifei F Deng Fei F Vlak Just M JM Hu Zhihong Z Wang Hualin H
Journal of virology 20080723 19
The GP64 and F proteins were previously identified as the sole functional envelope fusion proteins in Baculoviridae. F-like proteins, present only in group I nucleopolyhedroviruses (NPVs), are remnant, nonfunctional F proteins. In this report, we describe the effect of the presence or absence of the F-like protein Ac23 in a gp64-null Autographa californica multinucleocapsid NPV pseudotyped with the F protein from Spodoptera exigua multicapsid NPV (SeF). We found that the presence of Ac23 elevate ...[more]
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