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An amino acid substitution at position 740 in sigma70 of Ralstonia solanacearum strain OE1-1 affects its in planta growth.


ABSTRACT: Growth of Ralstonia solanacearum strain OE1-1 in roots after invasion is required for virulence. An Arg740Cys substitution in sigma(70) of OE1-1 resulted in loss of in planta growth and virulence. The negative dominance of mutant sigma(70) over the wild-type protein suggested that the amino acid substitution may affect the in planta growth of OE1-1, leading to a lack of virulence.

SUBMITTER: Kanda A 

PROVIDER: S-EPMC2547024 | biostudies-literature | 2008 Sep

REPOSITORIES: biostudies-literature

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An amino acid substitution at position 740 in sigma70 of Ralstonia solanacearum strain OE1-1 affects its in planta growth.

Kanda Ayami A   Tsuneishi Kazuhiro K   Mori Ai A   Ohnishi Kouhei K   Kiba Akinori A   Hikichi Yasufumi Y  

Applied and environmental microbiology 20080718 18


Growth of Ralstonia solanacearum strain OE1-1 in roots after invasion is required for virulence. An Arg740Cys substitution in sigma(70) of OE1-1 resulted in loss of in planta growth and virulence. The negative dominance of mutant sigma(70) over the wild-type protein suggested that the amino acid substitution may affect the in planta growth of OE1-1, leading to a lack of virulence. ...[more]

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