Ontology highlight
ABSTRACT:
SUBMITTER: Su D
PROVIDER: S-EPMC2553063 | biostudies-literature | 2008
REPOSITORIES: biostudies-literature
Su Dongju D Zhang Ximei X Sui Hong H Lü Fuzhen F Jin Lianhong L Zhang Jing J
BMC medical genetics 20080909
<h4>Background</h4>Rhinitis and asthma are very common diseases involving genetic and environmental factors. Most patients with asthma also have rhinitis, which suggests the concept of 'one airway, one disease.' A disintegrin and metalloproteinase 33 (ADAM33) is the first asthma-susceptible gene to be discovered by positional cloning. To evaluate the potential influence of ADAM33 gene polymorphisms on allergic rhinitis (AR) and allergic asthma (AS), a case-control study was conducted on the Han ...[more]